Phenothiazines

Phenothiazine | C12H9NS | CID 7108 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ... Aug 01, 2022 · Phenothiazines are used to treat serious mental and emotional disorders, including schizophrenia and other psychotic disorders. Some are used also to control agitation in certain patients, severe nausea and vomiting, severe hiccups, and moderate to severe pain in some hospitalized patients. Phenothiazines permit smoother induction of anaesthetic agents and allow treatment of behavioural symptoms secondary to Alzheimer's and senile dementia. Some phenothiazines exert an antipruritic effect. They are helpful for the treatment of neurodermatitis and pruriginous eczema and may relieve psychogenic itching. The Medical Use of ...Phenothiazine Definition A class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis. We and our partners store and/or access information on a device, such as cookies and process personal data, such as unique identifiers and standard information sent by a device for personalised ads and content, ad and content measurement, and audience insights, as well as to develop and improve products. 翻译 API; 关于 MyMemory; 登录 ... phenothiazine ( ˌfiːnəʊˈθaɪəziːn) n 1. (Elements & Compounds) a colourless to light yellow insoluble crystalline compound used as an anthelmintic for livestock and in insecticides. Formula: C12H9NS 2. (Pharmacology) any of several drugs derived from phenothiazine and used as strong tranquillizers and in the treatment of schizophrenia Phenothiazine Tranquilizers The most commonly used phenothiazines in veterinary medicine are acepromazine, chlorpromazine, and promazine. In domestic animals, they are used as tranquilizers, preanesthetic agents, antiemetics, and for treatment of CNS agitation after specific drug overdoses (amphetamines, cocaine). Phenothiazine drugs are primarily used for the treatment of schizophrenia and other forms of psychosis. Medications in this family include Chlorpromazine hydrochloride (Thorazine) Fluphenazine (Permitil, Prolixin) Mesoridazine besylate (Serentil) Perphenazine (Trilafon) Prochlorperazine (Compazine) Promazine hydrochloride (Sparine) Mar 29, 2021 · Phenothiazine: One of a group of tranquilizing drugs with antipsychotic actions thought to act by blocking dopaminergic transmission (messages sent using the substance dopamine) within the brain. 144hz ips monitor Phenothiazines have been used in many areas of medicine, mainly in psychopharmacology. These compounds are able to effectively inhibit dopamine, histamine, serotonin, acetylcholine, and α-adrenergic receptors; thus, their effect and side-effect profiles are extremely diverse. Besides their antipsychotic activity, phenothiazines have a ...Phenothiazines are a class of first-generation heterocyclic anti-psychotic medications, which display antagonistic activity towards dopamine receptors and recently have been shown to have potential anti-neoplastic properties. This activity illustrates the indications, action, and contraindications for phenothiazine as a valuable agent in treating and managing severe mental disorders such as ...In addition to D2 receptors, phenothiazines block the activity of H1 histamine receptors and M1 muscarinic receptors which stimulate GI smooth muscle contraction. Phenothiazine antipsychotics also depress the release of hormones by the hypothalamus and pituitary gland , which stimulate other glands in the body to release hormones.phenothiazine. ( ˌfiːnəʊˈθaɪəziːn) n. 1. (Elements & Compounds) a colourless to light yellow insoluble crystalline compound used as an anthelmintic for livestock and in insecticides. Formula: C12H9NS. 2. (Pharmacology) any of several drugs derived from phenothiazine and used as strong tranquillizers and in the treatment of schizophrenia. Phenothiazines • Thioridazine is used to treat schizophrenia and related psychoses. The normal daily dose is 150–600 mg. Doses that exceed 800 mg/day for just a few weeks may be sufficient to cause reduced VA and impairment of dark adaptation. Progressive retinal toxicity can occur ( Fig. 21.5 ): Phenothiazines can cause increased sensitivity to the sun. Various herbs, including St. John's wort and dong quai, can also cause this problem. Combined treatment with herb and drug might increase the risk further. YohimbePossible Dangerous Interaction The herb yohimbe is relatively toxic, and can cause problems if used incorrectly. Apr 07, 2013 · PHENOTHIAZINES: "Phenothiazines come in a variety of forms, making different methods of administration rather simple." Related Psychology Terms. Properties and uses: It is a white or almost white crystalline powder, slightly hygroscopic in nature. It is well soluble in water, alcohol, and methylene chloride. It has low clinical potency, medium extrapyramidal toxicity, high sedative effect, and high hypotensive action. It is used as dopamine receptor antagonist and neuroleptic. Phenothiazines "Phenothiazines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Aug 01, 2022 · Phenothiazines are used to treat serious mental and emotional disorders, including schizophrenia and other psychotic disorders. Some are used also to control agitation in certain patients, severe nausea and vomiting, severe hiccups, and moderate to severe pain in some hospitalized patients. Apr 07, 2013 · PHENOTHIAZINES By N., Sam M.S. - 14 a set of chemically corresponding substances, the majority of which are utilized as antipsychotic drugs, initially cultivated as such in the 1950's. The drugs in this category of classic antipsychotics were once the most widely utilized drugs for the remediation of schizophrenia. phenothiazine [ fē′nō-thī ′ə-zēn′ ] A yellow or green, toxic organic compound used in insecticides and dyes and to treat infections with worms and other parasites in livestock. Chemical formula: C12H9NS. Any of a group of drugs derived from this compound. Apr 11, 2020 · Phenothiazine is a class of drug that is used to treat mental disorders or psychotic disorders. But there’s more. And this is what we are discussing in this post. We try to cover the uses, side effects, the process of synthesis and the mechanism of action of Phenothiazine on the human body. General description. Phenothiazine is a versatile building block that can be easily functionalized as it possesses multiple modification sites. Its unique butterfly configuration and electron-rich character are beneficial for its potential use in optoelectronic applications. As it can undergo fast and reversible electron transfer reactions, it ...What is Phenothiazine? Alternately known as PTZ, phenothiazine is an organic compound with the chemical formula – S (C6H4)2NH. The compound has a connection to the thiazine class of heterocyclic compounds. The derivatives of phenothiazine are highly bioactive. They also have a history of widespread use. Phenothiazine, abbreviated PTZ, is an organic compound that has the formula S(C 6 H 4) 2 NH and is related to the thiazine-class of heterocyclic compounds.Derivatives of phenothiazine are highly bioactive and have widespread use and rich history. The derivatives chlorpromazine and promethazine revolutionized the fields of psychiatry and allergy treatment, respectively.Phenothiazine drugs are primarily used for the treatment of schizophrenia and other forms of psychosis. Medications in this family include Chlorpromazine hydrochloride (Thorazine) Fluphenazine (Permitil, Prolixin) Mesoridazine besylate (Serentil) Perphenazine (Trilafon) Prochlorperazine (Compazine) Promazine hydrochloride (Sparine) Mar 29, 2021 · Phenothiazine: One of a group of tranquilizing drugs with antipsychotic actions thought to act by blocking dopaminergic transmission (messages sent using the substance dopamine) within the brain. Phenothiazine | C12H9NS | CID 7108 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ...phenothiazine [ fē′nō-thī ′ə-zēn′ ] A yellow or green, toxic organic compound used in insecticides and dyes and to treat infections with worms and other parasites in livestock. Chemical formula: C12H9NS. Any of a group of drugs derived from this compound. best razor for shaving head phenothiazine ( ˌfiːnəʊˈθaɪəziːn) n 1. (Elements & Compounds) a colourless to light yellow insoluble crystalline compound used as an anthelmintic for livestock and in insecticides. Formula: C12H9NS 2. (Pharmacology) any of several drugs derived from phenothiazine and used as strong tranquillizers and in the treatment of schizophrenia phenothiazine ( ˌfiːnəʊˈθaɪəziːn) n 1. (Elements & Compounds) a colourless to light yellow insoluble crystalline compound used as an anthelmintic for livestock and in insecticides. Formula: C12H9NS 2. (Pharmacology) any of several drugs derived from phenothiazine and used as strong tranquillizers and in the treatment of schizophrenia Some phenothiazines (such as prochlorperazine and chlorpromazine) are also effective at relieving other symptoms unrelated to psychosis, such as nausea, vomiting, prolonged hiccups, tetanus symptoms and hyper-excitable behavior in children. List of Phenothiazine antipsychotics:Phenothiazines are a class of first-generation heterocyclic anti-psychotic medications, which display antagonistic activity towards dopamine receptors and recently have been shown to have potential anti-neoplastic properties. This activity illustrates the indications, action, and contraindications for phenothiazine as a valuable agent in treating and managing severe mental disorders such as ...Phenothiazines can cause increased sensitivity to the sun. Various herbs, including St. John's wort and dong quai, can also cause this problem. Combined treatment with herb and drug might increase the risk further. YohimbePossible Dangerous Interaction The herb yohimbe is relatively toxic, and can cause problems if used incorrectly. What is Phenothiazine? Alternately known as PTZ, phenothiazine is an organic compound with the chemical formula – S (C6H4)2NH. The compound has a connection to the thiazine class of heterocyclic compounds. The derivatives of phenothiazine are highly bioactive. They also have a history of widespread use. Apr 07, 2013 · PHENOTHIAZINES By N., Sam M.S. - 14 a set of chemically corresponding substances, the majority of which are utilized as antipsychotic drugs, initially cultivated as such in the 1950's. The drugs in this category of classic antipsychotics were once the most widely utilized drugs for the remediation of schizophrenia. Phenothiazines can cause increased sensitivity to the sun. Various herbs, including St. John's wort and dong quai, can also cause this problem. Combined treatment with herb and drug might increase the risk further. YohimbePossible Dangerous Interaction The herb yohimbe is relatively toxic, and can cause problems if used incorrectly. nj transit train schedule app Abstract. Rooted in the early days of organic dye chemistry, the phenothiazine structure and its derivatives have since held a prominent place in pharmacology and biomedicine. Initially used for histochemical stains of plasmodia by Paul Ehrlich, anthelmintic and antibiotic properties of phenothiazines were globally exploited in the 1930s and 1940s.Phenothiazine is an aromatic tricyclic compound that first emerged from the furtive chemical activity surrounding the aniline dye industry at the latter half of the 19th century. It contains both nitrogen and sulphur atoms and is the parent molecule of a multitude of drugs that have enjoyed varied a …Phenothiazines • Thioridazine is used to treat schizophrenia and related psychoses. The normal daily dose is 150–600 mg. Doses that exceed 800 mg/day for just a few weeks may be sufficient to cause reduced VA and impairment of dark adaptation. Progressive retinal toxicity can occur ( Fig. 21.5 ): Phenothiazines can cause increased sensitivity to the sun. Various herbs, including St. John's wort and dong quai, can also cause this problem. Combined treatment with herb and drug might increase the risk further. YohimbePossible Dangerous Interaction The herb yohimbe is relatively toxic, and can cause problems if used incorrectly. ...What drugs affect the sense of smell? Intranasal zinc products, decongestant nose sprays, and certain oral drugs, such as nifedipine and phenothiazines, are examples of drugs that may cause permanent loss of smell. Anosmia may also result from diseases of the nerve pathways that transmit smells to the brain. Why does smell bypass the thalamus? for example, n -phenylbenzo [ b ]phenothiazine ( 9) has been reported, which featured a nearly 50 nm red-shifted absorption relative to 3, allowing it to absorb in the visible region. 37 additionally, methods to synthesize visible-light-absorbing phens derivatives by substitution of the phens core with 4- n -butylphenyl groups (pcs 10 and 11) … Phenothiazines. General synthesis of propyl dialkylamino side chain derivatives. Synthesis. a. Promazine. Properties and uses: It is a white or almost white crystalline powder, slightly hygroscopic in nature. It is well soluble in water, alcohol, and methylene chloride. Mar 29, 2021 · Phenothiazine: One of a group of tranquilizing drugs with antipsychotic actions thought to act by blocking dopaminergic transmission (messages sent using the substance dopamine) within the brain. See full list on drugs.com copper fit socks compression phenothiazine ( ˌfiːnəʊˈθaɪəziːn) n 1. (Elements & Compounds) a colourless to light yellow insoluble crystalline compound used as an anthelmintic for livestock and in insecticides. Formula: C12H9NS 2. (Pharmacology) any of several drugs derived from phenothiazine and used as strong tranquillizers and in the treatment of schizophrenia Jan 10, 2022 · Phenothiazine antipsychotics are medications used in the treatment of schizophrenia and other psychotic disorders. Some of the phenothiazine antipsychotics are used for sedation and to treat severe hiccups, nausea and vomiting. Aug 01, 2022 · Phenothiazines pass into breast milk and may cause drowsiness or unusual muscle movements in the nursing baby. It may be necessary for you to take a different medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor. Drug Interactions Phenothiazines are a class of first-generation heterocyclic anti-psychotic medications, which display antagonistic activity towards dopamine receptors and recently have been shown to have potential anti-neoplastic properties. This activity illustrates the indications, action, and contraindications for phenothiazine as a valuable agent in treating and managing severe mental disorders such as ...Properties and uses: It is a white or almost white crystalline powder, slightly hygroscopic in nature. It is well soluble in water, alcohol, and methylene chloride. It has low clinical potency, medium extrapyramidal toxicity, high sedative effect, and high hypotensive action. It is used as dopamine receptor antagonist and neuroleptic. Properties and uses: It is a white or almost white crystalline powder, slightly hygroscopic in nature. It is well soluble in water, alcohol, and methylene chloride. It has low clinical potency, medium extrapyramidal toxicity, high sedative effect, and high hypotensive action. It is used as dopamine receptor antagonist and neuroleptic. Apr 07, 2013 · PHENOTHIAZINES: "Phenothiazines come in a variety of forms, making different methods of administration rather simple." Related Psychology Terms. Properties and uses: It is a white or almost white crystalline powder, slightly hygroscopic in nature. It is well soluble in water, alcohol, and methylene chloride. It has low clinical potency, medium extrapyramidal toxicity, high sedative effect, and high hypotensive action. It is used as dopamine receptor antagonist and neuroleptic. Phenothiazines are neuroleptic agents that affect a variety of receptors including dopaminergic receptor sites. Chlorpromazine was the first of the phenothiazines used clinically as an antipsychotic. Phenothiazines are used to treat psychosis including schizophrenia; violent, agitated, disturbed behavior; and mania secondary to bipolar disorder. dodge avenger 2008nice truckAbstract. Phenothiazines are neuroleptic agents that affect a variety of receptors including dopaminergic receptor sites. Chlorpromazine was the first of the phenothiazines used clinically as an antipsychotic. Phenothiazines are used to treat psychosis including schizophrenia; violent, agitated, disturbed behavior; and mania secondary to ...Phenothiazines can cause increased sensitivity to the sun. Various herbs, including St. John's wort and dong quai, can also cause this problem. Combined treatment with herb and drug might increase the risk further. YohimbePossible Dangerous Interaction The herb yohimbe is relatively toxic, and can cause problems if used incorrectly. ...Morphine Sulfate Injection is indicated for the relief of both acute and chronic severe pain, where continuous analgesia is required over several days following major surgical procedures, by Patient Controlled Analgesia (PCA). 4.2 Posology and method of administration Posology Adults and Children over 12 years phenothiazine ( ˌfiːnəʊˈθaɪəziːn) n 1. (Elements & Compounds) a colourless to light yellow insoluble crystalline compound used as an anthelmintic for livestock and in insecticides. Formula: C12H9NS 2. (Pharmacology) any of several drugs derived from phenothiazine and used as strong tranquillizers and in the treatment of schizophrenia Properties and uses: It is a white or almost white crystalline powder, slightly hygroscopic in nature. It is well soluble in water, alcohol, and methylene chloride. It has low clinical potency, medium extrapyramidal toxicity, high sedative effect, and high hypotensive action. It is used as dopamine receptor antagonist and neuroleptic. phenothiazine (fē′nō-thī′ə-zēn′, -nə-) n. 1. A yellow organic compound, C 12 H 9NS, used in insecticides, livestock anthelmintics, and dyes. 2. Any of a group of drugs derived from this compound and used in the treatment of psychiatric disorders, such as schizophrenia. Apr 11, 2020 · Phenothiazine is a class of drug that is used to treat mental disorders or psychotic disorders. But there’s more. And this is what we are discussing in this post. We try to cover the uses, side effects, the process of synthesis and the mechanism of action of Phenothiazine on the human body. Phenothiazines are neuroleptic agents that affect a variety of receptors including dopaminergic receptor sites. Chlorpromazine was the first of the phenothiazines used clinically as an antipsychotic. Phenothiazines are used to treat psychosis including schizophrenia; violent, agitated, disturbed behavior; and mania secondary to bipolar disorder.What is Phenothiazine? Alternately known as PTZ, phenothiazine is an organic compound with the chemical formula – S (C6H4)2NH. The compound has a connection to the thiazine class of heterocyclic compounds. The derivatives of phenothiazine are highly bioactive. They also have a history of widespread use. Apr 07, 2013 · PHENOTHIAZINES By N., Sam M.S. - 14 a set of chemically corresponding substances, the majority of which are utilized as antipsychotic drugs, initially cultivated as such in the 1950's. The drugs in this category of classic antipsychotics were once the most widely utilized drugs for the remediation of schizophrenia. Phenothiazine | C12H9NS | CID 7108 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ... • The phenothiazines and structurally related thioxanthines, along with the butyrophenones (phenylbutylpiperadines), diphenylbutylpiperadines and the indolones comprise the socalled “typical” (conventional) antipsychotics. As a group, the typical antisychotics are dopamine receptor antagonists with a higher affinity for D2 over D1 receptors. tesla model y australia Aug 01, 2022 · Phenothiazines are used to treat serious mental and emotional disorders, including schizophrenia and other psychotic disorders. Some are used also to control agitation in certain patients, severe nausea and vomiting, severe hiccups, and moderate to severe pain in some hospitalized patients. May 29, 2022 · Phenothiazines are a group of nitrogen and sulfur-containing heterocyclic compounds, labeled as the first-generation typical antipsychotic medications used for the treatment of schizophrenia, bipolar disorders, control nausea and vomiting, and other psychotic disorders with delusional manifestations. phenothiazine. ( ˌfiːnəʊˈθaɪəziːn) n. 1. (Elements & Compounds) a colourless to light yellow insoluble crystalline compound used as an anthelmintic for livestock and in insecticides. Formula: C12H9NS. 2. (Pharmacology) any of several drugs derived from phenothiazine and used as strong tranquillizers and in the treatment of schizophrenia. Mar 29, 2021 · Phenothiazine: One of a group of tranquilizing drugs with antipsychotic actions thought to act by blocking dopaminergic transmission (messages sent using the substance dopamine) within the brain. Jan 10, 2022 · Phenothiazine antipsychotics are medications used in the treatment of schizophrenia and other psychotic disorders. Some of the phenothiazine antipsychotics are used for sedation and to treat severe hiccups, nausea and vomiting. Phenothiazines have been used in many areas of medicine, mainly in psychopharmacology. These compounds are able to effectively inhibit dopamine, histamine, serotonin, acetylcholine, and α-adrenergic receptors; thus, their effect and side-effect profiles are extremely diverse. Phenothiazines are neuroleptic agents that affect a variety of receptors including dopaminergic receptor sites. Chlorpromazine was the first of the phenothiazines used clinically as an antipsychotic. Phenothiazines are used to treat psychosis including schizophrenia; violent, agitated, disturbed behavior; and mania secondary to bipolar disorder. wegmans instacart Phenothiazine is a benzo derivative of thiazine now most commonly used as an intermediate chemical in the manufacture of various psychiatric drugs. It originally was developed as a synthetic dye in 1883 [1], and it was introduced by DuPont as an insecticide in 1935. [2] phenothiazine [ fē′nō-thī ′ə-zēn′ ] A yellow or green, toxic organic compound used in insecticides and dyes and to treat infections with worms and other parasites in livestock. Chemical formula: C12H9NS. Any of a group of drugs derived from this compound. phenothiazine (fē′nō-thī′ə-zēn′, -nə-) n. 1. A yellow organic compound, C 12 H 9NS, used in insecticides, livestock anthelmintics, and dyes. 2. Any of a group of drugs derived from this compound and used in the treatment of psychiatric disorders, such as schizophrenia. General anesthesia drugs . A general anesthetic (or anaesthetic) is a drug that can bring about a reversible loss of consciousness. Phenothiazines Phenothiazines are used to treat a variety of psychiatric conditions. The mechanism of action is central and peripheral dopaminergic blockade. Many of the phenothiazines have anticholinergic, α receptor-blocking, sodium channel-blocking, and potassium channel-blocking properties. phénothiazines. Questions fréquentes. Recherche d'information médicale. Techniques analytiques, diagnostiques, thérapeutiques et équipements 3 Phenothiazine is an aromatic tricyclic compound that first emerged from the furtive chemical activity surrounding the aniline dye industry at the latter half of the 19th century. It contains both nitrogen and sulphur atoms and is the parent molecule of a multitude of drugs that have enjoyed varied a …phenothiazine. ( ˌfiːnəʊˈθaɪəziːn) n. 1. (Elements & Compounds) a colourless to light yellow insoluble crystalline compound used as an anthelmintic for livestock and in insecticides. Formula: C12H9NS. 2. (Pharmacology) any of several drugs derived from phenothiazine and used as strong tranquillizers and in the treatment of schizophrenia. We and our partners store and/or access information on a device, such as cookies and process personal data, such as unique identifiers and standard information sent by a device for personalised ads and content, ad and content measurement, and audience insights, as well as to develop and improve products. What drugs affect the sense of smell? Intranasal zinc products, decongestant nose sprays, and certain oral drugs, such as nifedipine and phenothiazines, are examples of drugs that may cause permanent loss of smell. Anosmia may also result from diseases of the nerve pathways that transmit smells to the brain. Why does smell bypass the thalamus? Phenothiazines • Thioridazine is used to treat schizophrenia and related psychoses. The normal daily dose is 150–600 mg. Doses that exceed 800 mg/day for just a few weeks may be sufficient to cause reduced VA and impairment of dark adaptation. Progressive retinal toxicity can occur ( Fig. 21.5 ): Phenothiazines • Thioridazine is used to treat schizophrenia and related psychoses. The normal daily dose is 150–600 mg. Doses that exceed 800 mg/day for just a few weeks may be sufficient to cause reduced VA and impairment of dark adaptation. Progressive retinal toxicity can occur ( Fig. 21.5 ): 翻译 API; 关于 MyMemory; 登录 ... orvis dog bedsPhenothiazines are neuroleptic agents that affect a variety of receptors including dopaminergic receptor sites. Chlorpromazine was the first of the phenothiazines used clinically as an antipsychotic. Phenothiazines are used to treat psychosis including schizophrenia; violent, agitated, disturbed behavior; and mania secondary to bipolar disorder.General anesthesia drugs . A general anesthetic (or anaesthetic) is a drug that can bring about a reversible loss of consciousness. Properties and uses: It is a white or almost white crystalline powder, slightly hygroscopic in nature. It is well soluble in water, alcohol, and methylene chloride. It has low clinical potency, medium extrapyramidal toxicity, high sedative effect, and high hypotensive action. It is used as dopamine receptor antagonist and neuroleptic. 翻译 API; 关于 MyMemory; 登录 ... Phenothiazines. General synthesis of propyl dialkylamino side chain derivatives. Synthesis. a. Promazine. Properties and uses: It is a white or almost white crystalline powder, slightly hygroscopic in nature. It is well soluble in water, alcohol, and methylene chloride. Phenothiazine Definition A class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis. longhorn restaurantApr 07, 2013 · PHENOTHIAZINES: "Phenothiazines come in a variety of forms, making different methods of administration rather simple." Related Psychology Terms. phenothiazine (fē′nō-thī′ə-zēn′, -nə-) n. 1. A yellow organic compound, C 12 H 9NS, used in insecticides, livestock anthelmintics, and dyes. 2. Any of a group of drugs derived from this compound and used in the treatment of psychiatric disorders, such as schizophrenia. Phenothiazines are neuroleptic agents that affect a variety of receptors including dopaminergic receptor sites. Chlorpromazine was the first of the phenothiazines used clinically as an antipsychotic. Phenothiazines are used to treat psychosis including schizophrenia; violent, agitated, disturbed behavior; and mania secondary to bipolar disorder.Phenothiazine antiemetics are a type of medicine that may be used to relieve nausea and vomiting. They work by inhibiting dopamine, muscarinic and histamine (H1) receptors generally in the vomiting center and chemoreceptor trigger zone. Phenothiazine antiemetics are usually reserved for severe cases of nausea and vomiting that occur as a result ...Phenothiazine is a benzo derivative of thiazine now most commonly used as an intermediate chemical in the manufacture of various psychiatric drugs. It originally was developed as a synthetic dye in 1883 [1], and it was introduced by DuPont as an insecticide in 1935. [2] Abstract. Phenothiazines are neuroleptic agents that affect a variety of receptors including dopaminergic receptor sites. Chlorpromazine was the first of the phenothiazines used clinically as an antipsychotic. Phenothiazines are used to treat psychosis including schizophrenia; violent, agitated, disturbed behavior; and mania secondary to ...Phenothiazines can cause increased sensitivity to the sun. Various herbs, including St. John's wort and dong quai, can also cause this problem. Combined treatment with herb and drug might increase the risk further. YohimbePossible Dangerous Interaction The herb yohimbe is relatively toxic, and can cause problems if used incorrectly. Phenothiazine drugs are primarily used for the treatment of schizophrenia and other forms of psychosis. Medications in this family include Chlorpromazine hydrochloride (Thorazine) Fluphenazine (Permitil, Prolixin) Mesoridazine besylate (Serentil) Perphenazine (Trilafon) Prochlorperazine (Compazine) Promazine hydrochloride (Sparine) Phenothiazines. General synthesis of propyl dialkylamino side chain derivatives. Synthesis. a. Promazine. Properties and uses: It is a white or almost white crystalline powder, slightly hygroscopic in nature. It is well soluble in water, alcohol, and methylene chloride. Apr 07, 2013 · PHENOTHIAZINES: "Phenothiazines come in a variety of forms, making different methods of administration rather simple." Related Psychology Terms. quill grammar xa